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Daniel R Meldrum Selected Research

Type I Tumor Necrosis Factor Receptors

9/2010Ablation of TNF-alpha receptors influences mesenchymal stem cell-mediated cardiac protection against ischemia.
6/2010TNF receptor 2, not TNF receptor 1, enhances mesenchymal stem cell-mediated cardiac protection following acute ischemia.
3/2009Role of tumor necrosis factor receptor 1 in sex differences of stem cell mediated cardioprotection.
10/2008TNFR1 signaling resistance associated with female stem cell cytokine production is independent of TNFR2-mediated pathways.
9/2008Mechanisms of sex differences in TNFR2-mediated cardioprotection.
10/2007Activation of individual tumor necrosis factor receptors differentially affects stem cell growth factor and cytokine production.
9/2007Sex differences in endothelial STAT3 mediate sex differences in myocardial inflammation.
4/2007Deficiency of TNFR1 protects myocardium through SOCS3 and IL-6 but not p38 MAPK or IL-1beta.
1/2007Gender differences in injury induced mesenchymal stem cell apoptosis and VEGF, TNF, IL-6 expression: role of the 55 kDa TNF receptor (TNFR1).
7/2006Tumor necrosis factor receptor 1 signaling resistance in the female myocardium during ischemia.

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Daniel R Meldrum Research Topics

Disease

42Ischemia
03/2012 - 02/2002
24Hypoxia (Hypoxemia)
01/2010 - 07/2004
23Inflammation (Inflammations)
11/2011 - 12/2003
12Reperfusion Injury
10/2012 - 06/2003
9Myocardial Ischemia (Ischemic Heart Diseases)
11/2011 - 01/2005
9Sepsis (Septicemia)
11/2010 - 09/2004
7Ureteral Obstruction
11/2012 - 10/2004
7Acute Lung Injury
10/2010 - 07/2005
6Fibrosis (Cirrhosis)
11/2012 - 06/2004
6Pulmonary Hypertension
10/2010 - 11/2005
6Wounds and Injuries (Trauma)
07/2008 - 01/2005
5Infarction (Infarctions)
11/2011 - 10/2009
5Myocardial Infarction
03/2011 - 08/2007
5Cardiovascular Diseases (Cardiovascular Disease)
08/2010 - 12/2003
4Endotoxemia
09/2011 - 05/2005
3Shock
10/2010 - 07/2008
3Heart Diseases (Heart Disease)
08/2009 - 05/2006
3Heart Failure
04/2007 - 06/2003
2Ventricular Remodeling
11/2011 - 10/2009
2Acute Kidney Injury (Acute Renal Failure)
06/2011 - 02/2008
2Burns
07/2008 - 01/2005
2Cardiomegaly (Heart Hypertrophy)
07/2008 - 09/2006
2Hemorrhagic Shock
03/2008 - 04/2007
1Chronic Renal Insufficiency
07/2010
1Peripheral Vascular Diseases (Peripheral Vascular Disease)
07/2009
1Neurodegenerative Diseases (Neurodegenerative Disease)
07/2009
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
11/2008

Drug/Important Bio-Agent (IBA)

25Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2010 - 02/2002
22Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2012 - 12/2006
20CytokinesIBA
11/2011 - 06/2004
13Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2011 - 06/2004
11Estrogens (Estrogen)FDA Link
08/2010 - 12/2003
10Proteins (Proteins, Gene)FDA Link
11/2012 - 10/2004
10Type I Tumor Necrosis Factor ReceptorsIBA
09/2010 - 07/2006
9Interleukin-6 (Interleukin 6)IBA
05/2011 - 12/2005
8p38 Mitogen-Activated Protein KinasesIBA
03/2012 - 01/2005
7salicylhydroxamic acid (SHAM)IBA
11/2012 - 10/2004
7Testosterone (Sustanon)FDA Link
08/2009 - 12/2003
7Messenger RNA (mRNA)IBA
03/2008 - 10/2004
6Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
06/2010 - 07/2006
4Interleukin-18 (Interleukin 18)IBA
11/2012 - 07/2008
4Caspase 3 (Caspase-3)IBA
07/2010 - 12/2005
4EndotoxinsIBA
03/2008 - 12/2006
4NF-kappa B (NF-kB)IBA
03/2008 - 02/2003
4RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
03/2008 - 11/2005
3triphenyltetrazoliumIBA
11/2011 - 07/2010
3Interleukin-1 (Interleukin 1)IBA
03/2011 - 09/2005
3Phosphotransferases (Kinase)IBA
11/2010 - 08/2006
3Type II Tumor Necrosis Factor ReceptorsIBA
09/2010 - 10/2007
3LipopolysaccharidesIBA
08/2010 - 12/2006
3SteroidsIBA
04/2010 - 09/2007
3Estrogen Receptor betaIBA
07/2009 - 08/2008
3Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
06/2009 - 08/2007
3Estradiol (Delestrogen)FDA LinkGeneric
04/2009 - 05/2008
3Vasoconstrictor AgentsIBA
12/2008 - 07/2008
3Phenylephrine (Neo-Synephrine)FDA LinkGeneric
12/2008 - 01/2006
3Conditioned Culture MediaIBA
10/2008 - 06/2007
3Gonadal Steroid Hormones (Sex Hormones)IBA
05/2008 - 05/2005
3Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
01/2007 - 11/2005
2Transforming Growth Factors (Transforming Growth Factor)IBA
03/2012 - 11/2011
2Transforming Growth Factor alpha (TGF-alpha)IBA
08/2011 - 01/2010
2STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
08/2011 - 07/2009
2Interleukin-10 (Interleukin 10)IBA
08/2011 - 03/2011
2CollagenIBA
06/2011 - 09/2009
2Cadherins (E-Cadherin)IBA
06/2011 - 09/2009
2Transforming Growth Factor beta1 (TGF beta 1)IBA
09/2009 - 06/2004
2Androgen Receptors (Androgen Receptor)IBA
08/2009 - 01/2005
2Flutamide (Eulexin)FDA LinkGeneric
08/2009 - 01/2005
2Estrogen Receptor alphaIBA
07/2009 - 06/2006
2Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
06/2009 - 03/2008
2Glucose (Dextrose)FDA LinkGeneric
06/2009 - 02/2009
2Interleukin-1beta (Interleukin 1 beta)IBA
08/2008 - 12/2005
2Mitogen-Activated Protein KinasesIBA
07/2008 - 12/2005
2Ion Channels (Ion Channel)IBA
06/2006 - 07/2004
2rho-Associated KinasesIBA
06/2006 - 03/2006
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
11/2012
1oxalylglycineIBA
08/2011
1Epidermal Growth Factor (EGF)IBA
08/2011
1LigandsIBA
08/2011
1MimosineIBA
08/2011
1Anti-Arrhythmia AgentsIBA
08/2011
1statticIBA
08/2011
1HMGB1 Protein (HMG1)IBA
03/2011
1Toll-Like Receptors (Toll-Like Receptor)IBA
12/2010
1Vasodilator Agents (Vasodilators)IBA
10/2010
1IsofluraneFDA LinkGeneric
09/2010
1Coloring Agents (Dyes)IBA
07/2010
1Evans Blue (Blue, Evans)FDA Link
07/2010
1Toll-Like Receptor 2IBA
05/2010
1Carrier Proteins (Binding Protein)IBA
10/2009
1ChemokinesIBA
09/2009
1TIE-2 Receptor (Receptor, TIE 2)IBA
04/2009
1Angiopoietin-1IBA
04/2009
1Cytochromes c (Cytochrome c)IBA
12/2008

Therapy/Procedure

16Therapeutics
10/2012 - 07/2004
3Ligation
11/2011 - 10/2009
2Baths
01/2006 - 11/2005
1Intravenous Infusions
09/2011
1Artificial Respiration (Mechanical Ventilation)
10/2010
1Anesthesia
09/2010